Interleukin‐6 Signaling Mediates Human Muscle Satellite Cell Proliferation Following Acute Muscle Damage

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منابع مشابه

IL-6 Induced STAT3 Signalling Is Associated with the Proliferation of Human Muscle Satellite Cells Following Acute Muscle Damage

BACKGROUND Although the satellite cell (SC) is a key regulator of muscle growth during development and muscle adaptation following exercise, the regulation of human muscle SC function remains largely unexplored. STAT3 signalling mediated via interleukin-6 (IL-6) has recently come to the forefront as a potential regulator of SC proliferation. The early response of the SC population in human musc...

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Satellite Cell Proliferation in Adult Skeletal Muscle

England et al. (1990), Very mild muscular dystrophy associated with the deletion of 46% of dystrophin., Nature, 343:180-182. Gilboa et al. (1986), Transfer and Expression of Cloned Genes Using Retroviral Vectors., Biotechniques, 4(6):5O4-5 12. Allbrook, D. (1981), Skeletal Muscle Regeneration, Muscle and Nerve, 4:234-245. Ishiura et al. (1986), Biochemical Aspects of Bupivacaine-Induced Acute M...

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There are many known growth factors/cytokines that induce skeletal muscle satellite cell proliferation. Currently, the signaling mechanisms in which these growth factors/cytokines activate satellite cell proliferation are not completely understood. Here, we sought to determine signaling mechanisms by which leukemia inhibitory factor (LIF) induces satellite cell proliferation in culture. First, ...

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ژورنال

عنوان ژورنال: The FASEB Journal

سال: 2009

ISSN: 0892-6638,1530-6860

DOI: 10.1096/fasebj.23.1_supplement.601.7